Scientists have identified a new virus that caused the outbreak of a deadly pneumonia among monkeys at the California Primate Research Center, and found that it can be transmitted to humans and further between people, according to an article published in the journal PLoS Pathogens.
In May 2009, the California National Primate Research Center (California National Primate Research Center — CNPRC) outbreak galloping pneumonia, accompanied by hepatitis in South American monkeys — red jumpers (Callicebus cupreus). In 23 of the 65 monkeys developed pneumonia and hepatitis, and 19 of them, despite treatment, died or were euthanized. One of the center's employees and members of his family also became infected.
A team led by Charles Chu (Charles Chiu) from the University of California at San Francisco identified the virus that caused the outbreak. It was a previously unknown adenovirus, designated TMAdV (titi monkey adenovirus), a type of DNA viruses that can infect many vertebrates, including primates and humans.
"In general, as previously thought, adenovirus infection, is specific to each species" — the scientists say. Previous data showed that each type of adenovirus can infect only "their" look. Human adenoviruses do not replicate in monkey cells without special helper viruses and do not infect rodents and vice versa.
But this time, the virus crossed species boundary.
The study showed that at the Centre, who was in close contact with infected monkeys that had received acute respiratory disease, the virus is contracted TMAdV. In addition, it has infected by the same virus family members, who were not in contact with the monkeys.
Many are specific to certain types of viruses, including the bird flu virus can infect humans, but from person to person, they can not. TMAdV but in this case, has shown the ability to spread among the people: relatives center employee sick.
The authors note that the monkey can not be the natural reservoir of the virus, otherwise it would not have caused such a severe outbreak. Human adenovirus infections can lead to the death of approximately 18% of cases.
"Opening TMAdV, adenovirus can infect both man and apes, suggests that requires monitoring of adenovirus as a potential source of cross-species disease outbreaks," — concludes the author.
However, Chu said that there is no reason to fear a pandemic TMAdV, as is the case with other viruses, species had crossed the border. Analysis of 81 randomly selected sample of the blood supply in the United States found that only two samples have antibodies to the virus.
"The virus is passed into the human population for a long time and has since been circulating at low levels," — said Chu, whose words are quoted NatureNews.
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