According to scientists, the discovery of a new method for the early diagnosis of Alzheimer's can be started a new era in the treatment nevralyagichnay disease, which was long considered incurable. The method allows to accurately determine whether a patient has Alzheimer's disease and what are the chances of getting sick on it in the future. With appropriate therapy is probably not enough to stop the death of nerve cells — a process in which people lose the ability to remember, think and reason. Investigation of a new technique was published on Tuesday, in a U.S. medical journal "Archives of Neurology".
The clandestine nature of Alzheimer's
According to experts, the hardest part of Alzheimer's disease — its hidden nature. It may not manifest for decades, but meanwhile in the brain of the patient, irreversible changes. If there are obvious signs of dementsyi, too late to save the brain.
Another concern is the fact that Alzheimer's has significantly younger. If before it occurs predominantly in people over 65 years, now its symptoms are found in younger who's not yet 50. The man in front is somehow different — fussy, forgetfulness, can not concentrate on anything. Quite quickly lost experience and memory, acquired over a lifetime. Typically, this occurs when abnormal recovery of past experience. Very quickly destroyed the ability to make judgments and conclusions, abstract reasoning, to make comparisons. In intimate impression that patients have forgotten how to do the usual once the job for them. They can not wash clothes, clean the house, cook, shave, write. It is incomprehensible. In the later stages of Alzheimer's disease are observed seizures.
Today, in the world of Alzheimer's affects more than 26 million people. According to the World Health Organization, by 2050, the number of patients will increase by 275% to over 100 million. Serious treatments for Alzheimer's disease has so far not been found.
In search of amyloid plaques
As the Belgian professor Geert De Meyer, his colleagues managed to find a fairly simple and true method for early detection of Alzheimer's syndrome. In his view, the spine puncture Keyes and rentgenaskapiya brain — so-called PET (pazytronna emission tomography) — are able to identify the patient's presence of amyloid plaques, a unique feature of this disease.
"If the analysis shows spinnamazgavoy fluid suddenly a sharp increase in the number of beta-amiloidav and tau protein somewhere in the three-fold compared with the norm, we can talk about the development of pathology. Most important thing that we can recognize it at this early stage "- said de Meyer.
Published in the latest issue of the journal "Archives of Neurology" O Belgian scientists have caused mixed reactions of their colleagues.
Many experts point out that the results obtained in the course of the experiment in special clinical and laboratory conditions, it is unlikely to be achieved in conventional hospitals. It has been suggested that effective medicines that can eliminate amiloidnyya plaques will not today and not tomorrow.
Doctors anticipate the ethical problems associated with the ability to predict the progression of the disease in the too distant future.
The question is whether physicians should inform patients that their analyzes indicate a high risk of developing Alzheimer's disease. Majority of the votes — for the fact that it should be resolved between the doctor and the patient.
On Stephen Dekoski, Dean of the Medical School of the University Virzhynskaga, "This is what everyone is looking for — the absolute accuracy of the forecast."
Meanwhile, Michael Uayner, professor of medicine, radiology, psychiatry, and nevralegii at the University of San Francisco, said that the manifestation of the disease with spinnamazgavoy puncture and PET brain — a potentially effective means of diagnosis. After all, so far the most accurate diagnosis of the disease was achieved with patolyagaanatamichnym study.
Professor Uayner also hoped that the work of Belgian scientists will give an impetus to the creation of a modern and effective treatment of this disease.