How stem cells treat coronary heart disease?

Few patients Coronary heart disease (CHD) aware of the fact that their condition can not only stabilize the drug intake, but largely reversed, and it is absolutely natural way. That is, to improve blood flow to the heart, so that it once again to perform his function.

When cardiac function recovered, a person does not have to worry about the limits of their everyday opportunities: how can pass, how long you can work, can I have sex, etc. Reduced or are anginal pain, reduced working capacity and the ability to lead a normal sex life, and thus returning cheerfulness, good humor and satisfaction with life.

At first glance, it sounds fantastic, but, nevertheless, such a method of treatment exists, and not only in the western experimental laboratories, but also in Russian clinics. This is — stem cell treatment.

It is not only combined with other types of treatment, but also increases their efficiency. In most cases this therapy significantly reduces the number and dose of drugs taken. Furthermore, it is effective prevention of myocardial infarction.

How does this work

Ischemia is a condition in which blood oxygen brought in is not enough to meet the needs of the body. In CHD anoxia experiencing extremely sensitive to it body — the heart. With a lack of blood supply, it can not properly perform their functions and, therefore, blood circulation throughout the body.

In most cases, the cause of CHD is narrowing cardiac arteries atherosclerotic plaques that are deposits of lipids (fats) in the vessel wall. Such deposits occur due to metabolic disorders, malnutrition, and inadequate physical activity, that is the typical "life partners" inhabitants of the modern world.

For the treatment of coronary artery disease using drugs dilate the arteries of the heart, reducing myocardial oxygen demand, prevent the formation of blood clots (blood clots) and normalizing lipid metabolism, and taking these medicines should be for life. In more severe cases, surgery is required — the expansion of the heart arteries metal "inserts" (stents) or the imposition of artificial vessels (grafts) to bypass the affected area.

Both of these methods, but also help to significantly improve the human condition and prolong his life, not perfect.

Medication is not always possible to completely restore normal lipid metabolism and to ensure an adequate supply of blood to the heart (not to mention the fact that few patients comply with discipline rather complex patterns of admission). In addition, there are contraindications to medications. The operation also solves the problem for any given area of the vessel, without hindering the further development of atherosclerosis on the other.

Rid of these shortcomings treatment stem cells. It is to run a natural process of repairing damaged heart tissue and the growth of new blood vessels that supply it with blood.

Stem cell treatment starts with a set of analyzes and other studies that high reliability can determine whether it is appropriate to a specific person. If the answer to this question is positive, the patient taking the cell culture (typically from bone marrow or adipose tissue) isolated therefrom and mesenchymal stem cells.

The feature of these cells is that they, unlike other cells of the organism, are not expressed traits defining their function, i.e. they can not be attributed to any specific tissues (nerve, muscle, etc.). But stem cells have two important characteristics — they are able to recognize the damage the organ or tissue and develop into virtually any cell type necessary for their recovery.

The largest number of stem cells and their best "performance" are observed in the growing organism, that is, in children. With age, the quantity and quality of these cells is reduced — which is why authorities gradually "wear out", which is the basis of age-related changes.

For example, in a neonatal bone marrow stem cell accounted for 10,000 of hematopoietic, a teenager — to 100,000 in 50 years — to 500,000, while 70-year-old — a million. However, these cells do not completely disappear ever, which means that they can be isolated and propagated to activate.

That is what happens in the next step of treatment. Obtained from a patient mesenchymal stem cells were grown for two weeks in an incubator for waste and the highest worldwide technology. During this time, their number reaches a minimum of 200 million.

Then for another one week, part of these cells is subjected to partial differentiation — Development progenitor cells required tissue preserving a limited ability to transform the cell type to another. In the case of the heart such partially differentiated cells are cardiomyoblast — progenitor cells of cardiac muscle fibers.

When the cells are grown, a mixture of mesenchymal stem cells and cardiomyoblast intravenously administered to humans, because the whole venous blood goes directly to the heart. Upon arrival at their destination, the stem cells themselves recognize the damage and begin to work with each of them gives rise to a whole "family" (pool) of new cells. In the short term, "offspring" imposed by trillions of cells that makes up for natural losses in the last 10-15 years.


A sample of mesenchymal stem cells from the patient is kept in pozhizneno Cryobank clinic stem cell "Contemporary Medicine", which is "biological insurance" — at any time of life can grow the number of cells needed to treat.


In rebuilding the damage involves not only grown cells — they also secrete specific "signal" molecules that activate stem cells in the affected organ. In this part of the injected cells are reserved by the body in special depots that exist in all organs and tissues.

The result of treatment is to promote atherosclerotic vascular walls, restoration of damaged areas of the myocardium and formation in the heart of an extensive network of communicating with each other new vessels — collaterals. Thanks to them the blood flow to the heart muscle is significantly increased, and hence its oxygen starvation is reduced or eliminated altogether.

Strengthening of the old growth of new blood vessels and prevent the development of severe complications coronary artery disease — myocardial infarction. This condition occurs when, due to the destruction of the atherosclerotic plaque is formed thrombus completely closing the lumen of one of the vessels of the heart and leads to the death of the corresponding section of the myocardium. After stem cell treatment the probability of failure is significantly reduced plaque formation, but even if that happens, the network will continue to provide collateral blood all the heart muscle.

Where to come to be treated?

In Russia license for stem cell therapy has only one institution — Clinic stem cells "Contemporary Medicine" in Moscow. Equipment and techniques used in it are certified by national and international standards, and all staff have extensive experience in working with stem cells obtained at the stage of laboratory experiments and clinical trials.

Because the clinic is interested in the development of modern medicine — stem cell therapy, each patient thoroughly examined before treatment and carefully monitored by the individual program in the process of therapy and after that the effectiveness of the treatment was the highest, and there were no complications.

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