Longevity runs in families

Centenarians. Why do some people live much longer than the average years — a question that is haunted by scientists around the world. At this time the mysterious nature of the phenomenon of longevity tried to decipher the Dutch researchers.

A group of researchers from the oldest in the Netherlands, Leiden University, led by Dr. Diana Van Hemst carefully examined the data 380 European families. Each of them was with at least two long-lived relative to the age of about 90 years. The details of this research project can be read in the Canadian Medical Association Journal.

Attracted the attention of scientists, above all, brothers, sisters and children of centenarians. In addition, data were examined partners — both carriers themselves "longevity gene" and their children. We examined more than a thousand (1,038) children, and 461 people came to the control group.

The discovery, which was made by scientists on the basis of these data, it turned out quite paradoxical, and it seems even more thickened the veil of secrecy around the phenomenon of longevity. The researchers concluded that an inherited longevity associated with low levels of vitamin D in the body, as well as changes in a specific gene. In this case, the Dutch measured the vitamin D levels of 25, according to their seasonal fluctuations. In addition, were taken into account influencing factors indicators of vitamin D — solarium, age, gender, body mass index, consumption of vitamins, renal and genetic features of the vitamin by the body making each participant experiment.

"We found that the offspring of centenarians who had at least one 90-year-old brother or sister, had low levels of vitamin D compared with the control group, regardless of the possible adverse factors" — are contained in the article, the words of scientists. The researchers also point to the fact that the offspring of centenarians are much less common form of the gene CYP2R1, is responsible for the body's ability to store large amounts of vitamin D.

The paradox is that low vitamin D is associated with high mortality, cardiovascular disease, cancer, allergies, disorders of intelligence. How does the lack of it prolongs life — another mystery that scientists have yet to unravel.

For the record:

Vitamin D is involved in the regulation of cell proliferation and tissue regulates metabolic processes in the body stimulates the synthesis of a number of hormones play an important role in maintaining the activity of the cardiovascular system, liver, pancreas, gastrointestinal tract. Vitamin D metabolites regulate the transport of calcium in the body, providing a major impact on the formation and maintenance of bone tissue. Also, the vitamin D regulates absorption of calcium and phosphorus levels in bone and teeth. Together with vitamin A and calcium or phosphorus protects the body from cold, influenza, diabetes, skin and eye diseases.

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