IVF: How to minimize risk

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"Children — flowers of life." Ironically, the meaning of this phrase conventional wisdom is best understood not mothers with many children, and women who are about pregnancy can only dream of. According to statistics, a lot of these in Russia — 10-15%.

But there is good news. If the time to seek professional help, in 95% of cases of infertility can result … the long-awaited birth of the baby. And last but not play a role in this assisted reproductive technology.

How, despite the disappointing diagnosis, to help a woman become a mother? What is in vitro fertilization (IVF), which are still assisted reproductive techniques? How to improve their performance, and hence the probability of a wanted pregnancy, with minimal risk for the patient? These and other questions are answered reproductive health clinic specialists "Flowers of Life": Chief Medical Officer, obstetrician-gynecologist reproductologist, MD Oksana V. Starkov andobstetrician-gynecologist PhD Nicholas A. MATVEEVSKIY.

— For most people, IVF is associated with the children out of the tube. Is that true?

OV Starkov: So think of those who did not faced with the problem of infertility. The couple, who for years could not conceive a child and consciously come to the conclusion that they need IVF, understand what they mean.

NA MATVEEVSKIY: But, in fact, ordinary people are right. IVF — a technique from the arsenal of assisted reproductive technology, which includes a fence egg, its fertilization in an artificial environment outside the body and transferring the embryo into the uterus.

OV Starkov: Just do not think that assisted reproductive technologies are limited to IVF. There is also a Wii (intrauterine artificial insemination), ICSI (introtsitoplazmaticheskaya sperm injection), PGD (preimplantation genetic diagnosis) and other methods. Our task — to help women achieve a long-awaited pregnancy. And it is very important to choose the method which, on the one hand, will be most effective, and on the other — it is ideally suited to this patient. In each case, everything is solved individually, taking into account many factors, primarily the causes of infertility.

— Does IVF couples with unexplained infertility?

OV Starkov: The diagnosis of "idiopathic" or unexplained infertility means that modern methods of examination in this case did not establish the cause of impaired fertility. Such pairs recommend IVF — and as a means of treatment, and as a diagnostic method, as it becomes possible to directly study the interaction of sperm and egg, and embryo quality.

— Suppose, for you to come to the reception a couple who dreams of a child. Tell us what they have to?

OV Starkov: At first the woman and the man are full examination to establish the causes of infertility. We must identify the indications and contraindications for IVF.

NA MATVEEVSKIY: If there is a contraindication for women of pregnancy, acute inflammatory processes in the body are benign tumors and malignant genital any location, IVF can not be carried.

— If the survey found that IVF patient shows what happens next?

Clinic for Reproductive Health "Flowers of Life"

  • Treatment of infertility
  • IVF
  • ICSI
  • Surrogacy

OV Starkov: When this form of infertility does not require additional treatment (and this is quite rare), we select the assisted reproductive technique and begin to act.

— Many women are hesitant to IVF because the stimulation of superovulation have to take large doses of hormones. But this is bad for the body

OV Starkov: Indeed, there is a problem. And every medical center decides itsin its own way. We, the specialists of the clinic reproductive health "Flower of Life", focus on the rejection of the introduction of excess hormones and try to work on minimal stimulation. And if possible, prefer to carry out IVF in the natural cycle.

— But it does not reduce the efficiency of the method?

OV Starkov: This is how you look. Generally the effectiveness of IVF varies clinic where it is held. A very important factor is the age of the woman and her ovarian reserve. With minimal stimulation is obtained only 1-2 eggs, which, of course, reduces the amount of material for IVF. On the other hand, as we are protecting the health of the patients of ovarian hyperstimulation syndrome. Also, avoid excess hormones and the approach to the natural cycle of women create optimal conditions for the onset of pregnancy. The body does not struggle with the complications of hyperstimulation, and sends all the power to the unborn child.

NA MATVEEVSKIY: Today doctors Reproduction all over the world tend to minimal stimulation. The main task — to combine the maximum chance of pregnancy with minimal stimulation.

— Andafter all, if you enter into the cavity of the uterus, for example, 4-5 embryos, the chances of conception should be increased?

NA MATVEEVSKIY: Yes, they are rising. But it is growing and the likelihood of multiple births, which is fraught with serious complications — both for the woman and for pregnancy. If you can not make it, and then, as a rule, children are born prematurely, weak. So, for two years, as the transfer of more than 3 embryos in IVF is officially banned.

— Are there ways to increase the chances of pregnancy with IVF?

OV Starkov: Unfortunately, the panacea to guarantee a pregnancy for any woman with a diagnosis of "infertility", not there yet. It is very individual and depends on the causes of reproductive disorders. The odds go up if you can figure out at what level there was a "failure", and ideally — to remove it. And there are of paramount importance the experience and professionalism of doctors.

For example, if a woman or her husband is a good chance to pass to the unborn baby inherited disease before transfer of the embryo into the uterus is necessary to pre-implantation genetic diagnosis for chromosomal abnormalities or mutations of genes. This allows you to weed out those embryos that were originally not viable, and use only high-grade, so the chances of pregnancy also increases.

— And how do you feel about the cryopreservation?

NA MATVEEVSKIY: Today, many hospitals, including ours, offer such a service. It allows the preparation of a large number of embryos remaining cryopreserved. In simple terms — to freeze and store the required amount of time. The main advantage of cryopreservation, if the first time has not given IVF outcome, in the next cycle is ready to carry embryos, and hence stimulation is not necessary for their production and recovery operation.

— So, your mission is accomplished — a woman pregnant. What's next?

OV Starkov: Up to 12 weeks after IVF we will do "conduct" the patient. At her desire, our experts can continue to maintain the pregnancy until 36 weeks, up to the hospital. This is the preferred option because not all doctors in the women's consultations may be aware of the peculiarities of pregnancy after in vitro fertilization. There are, for example, special preparations are important to add time or, alternatively, to cancel. Doctor on IVF is obliged to observe his patient until he sees her baby's heartbeat.

Thanks for the interesting and informative conversation. It remains to wish all patients of reproductive health clinics "Flowers of Life" to fulfill his dream and bec
ome happy parents.

Source: Go toLinik reproductive health "Flowers of Life"

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