Siberian scientists have deduced fearless rats

Genetic material from the laboratory of the American biochemist, Nobel laureate Robert Lefkowitz Novosibirsk scientists helped bring the party fearless rats.

This was today told reporters neyrogenomiki functional head of the laboratory of the Institute of Cytology and Genetics, Russian Academy of Sciences Nikolai Dygalo.

The subject of the research of Nobel Laureates in Chemistry in 2012 by Robert Lefkowitz and Brian Kobilki are receptors coupled to G-proteins.

"In the early 90s I wrote Lefkowitz, and he sent me a plasmid, ie receptor gene, isolated separately. It was a difficult time, the plasmid while we lay there, but then we were able to use it and to suppress the expression of the gene neurotransmitters — norepinephrine, "- said Nikolai Dygalo.

In the experiment, the scientists artificially "locked" receptor rat and the animal lost a sense of fear.

"When the animal became an adult, it was fearless. This is very bad. In nature, such a person will eat quickly ", — Mykola Dygalo.

This study aims to examine the mechanism of the formation of mental disorders. According to Nikolai Dygalo such abnormalities may also occur in humans, their triggers, for example, the parent inattention to the baby.

FAQ: Americans Robert Lefkowitz (Robert Joseph Lefkowitz) and Brian Kobilka (Brian Kobilka) won the Nobel Prize in Chemistry for his work on the study of receptors coupled to G-protein (or receptor semispiralnyh). Because of these unique molecules, protein family spirals penetrating the cell membrane, we can feel, respond to external stimuli, and more.


I remember the Scandinavian war guzzle mushrooms to be fearless in combat, violent killers (Berserk). It seems to that and is a science in the creation of a soldier-fanatics.


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