Breast cancer — the most common cancer in women

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Many women more than any other disease apprehend breast cancer. Indeed, today it is indeed the most common type of cancer in women. According to the American Cancer Society are diagnosed worldwide each year 1.3 million new cases of breast cancer, and about five hundred thousand women die. However, over the last decade, mortality from breast cancer has decreased since significantly improve the quality of care, which in turn has led to earlier diagnosis of the disease in stages, when it can still be cured.

The basis of early detection of breast cancer — a regular survey (either alone or in mammologa) and medical research (X-ray mammography, ultrasound, magnetic resonance imaging).

Mammary gland: the milk ducts (dark blue), cloves (cyan), breast tumor (yellow education).

X-ray mammography

X-ray mammography is fairly accurate method of diagnosis, but like most medical procedures, it is not ideal. Studies have shown that the use of mammography is possible to pass 35% of malignant tumors, especially in women before menopause when the fabric breast dense enough. Furthermore, 5-10%, or there is a change in mammography unclear portions that require additional imaging techniques and or biopsy.

Ultrasound examination

Ultrasound (ultrasound) mammary glands can be used in combination with X-ray mammography diagnostics, including the monitoring of suspicious areas. This technique allows to distinguish between benign cysts of soft tissue structures. In the case of cysts do not need a biopsy and research resected tissue under a microscope.

Magnetic resonance imaging

In conventional mammography imaging of breast tissue applies X-rays and magnetic resonance — radio wave. When breast MRI requires intravenous contrast agent containing gadolinium. The introduction of a contrast agent to distinguish tumor from healthy breast tissue. Bayer Schering Parma has a wealth of experience in the development of contrast agents for magnetic resonance imaging. In 1988 the company released the first contrast agent for magnetic resonance imaging on the market. To date, the use of contrast agents for breast MRI has become the standard.

MRI allows us to solve problems of diagnosis in patients with dense breasts and unclear results of X-ray mammography. These comparisons with other methods of MRI radiology suggest that MRI is a highly sensitive method, surpassing others in detecting breast cancer and determining the stage of the disease.

Although breast MRI has a reputation as a method which often gives a large number of false-positive results, the experience shows that the use of computer programs and systems diagnostics BI-RADS (Data Acquisition System ray studies of the breast) can significantly improve the quality of diagnosis.

MRI screening is recommended to patients at high risk

The study of MR images of the breast

X-ray mammography

X-ray mammography is fairly accurate method of diagnosis, but like most medical procedures, it is not ideal. Studies have shown that the use of mammography is possible to pass 35% of malignant tumors, especially in women before menopause when the fabric breast dense enough. Furthermore, 5-10%, or there is a change in mammography unclear portions that require additional imaging techniques and or biopsy.

Ultrasound examination

Ultrasound (ultrasound) mammary glands can be used in combination with X-ray mammography diagnostics, including the monitoring of suspicious areas. This technique allows to distinguish between benign cysts of soft tissue structures. In the case of cysts do not need a biopsy and research resected tissue under a microscope.

Magnetic resonance imaging

In conventional mammography imaging of breast tissue applies X-rays and magnetic resonance — radio wave. When breast MRI requires intravenous contrast agent containing gadolinium. The introduction of a contrast agent to distinguish tumor from healthy breast tissue. Bayer Schering Parma has a wealth of experience in the development of contrast agents for magnetic resonance imaging. In 1988 the company released the first contrast agent for magnetic resonance imaging on the market. To date, the use of contrast agents for breast MRI has become the standard.

MRI allows us to solve problems of diagnosis in patients with dense breasts and unclear results of X-ray mammography. These comparisons with other methods of MRI radiology suggest that MRI is a highly sensitive method, surpassing others in detecting breast cancer and determining the stage of the disease.

Although breast MRI has a reputation as a method which often gives a large number of false-positive results, the experience shows that the use of computer programs and systems diagnostics BI-RADS (Data Acquisition System ray studies of the breast) can significantly improve the quality of diagnosis.

MRI screening is recommended to patients at high risk

In 2007, the American Cancer Society (ACS) has issued new guidelines for MRI screening in addition to mammography for women who have at least one of the following criteria:

  • the risk of breast cancer in their lifetime 20-25% or more;
  • Carriers of mutations of cancer genes breast: BRCA 1 and 2;
  • receiving radiotherapy to the chest over malignancies — e.g., lymphoma early;
  • presence of blood relatives or the patients themselves hereditary syndromes (Li-Fraumeni syndrome and Cowden).

Search for additional tumors in women with newly diagnosed breast cancer

For the majority of patients with breast cancer is high probability of the second chamber. Up to 20% of cancer patients have breast tumors another in the same or another iron, even if X-ray mammography examination and nothing is detected.

Studies have shown that MRI is able to identify the greatest number of contralateral cancers from the time of primary diagnosis of the primary tumor. As a result, anti-cancer therapy at the early stage can significantly improve the chances of the patient to full recovery.

Treatment of breast cancer and the use of MRI to monitor therapy

In recent years, there was literally a breakthrough cancer — there are new, life-saving techniques of treatment of cancer.

Treatment of breast cancer include surgery, radiation therapy, hormonal (antiestrogenic) therapy, chemotherapy, and immune therapy Target. None of these methods are not universal, suitable to each patient usually requires a combination therapy. The choice of treatment depends on many factors — the age of the patient, presence or absent of menopause, type of tumor, stage of the presence or absence of hormonal receptors on the surface of cancer cells. To monitor the effectiveness of treatment with magnetic resonance imaging is more effective compared with mammography and ultrasound. Moreover, with sparing surgery MRI allows to avoid local recurrence of the tumor.

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