Prenatal screening for trisomy I trimester of pregnancy (I trimester biochemical screening for pregnancy, "double test» I trimester) — complex research being undertaken to pregnant women to assess the risk of fetal abnormalities: Down syndrome (trisomy of chromosome 21), Edwards syndrome (trisomy 18), neural tube defects (NTDs).
What indicators are included in the "double test» I trimester?
- Human chorionic gonadotropin free (free hCG, free beta-hCG);
- Protein associated with pregnancy (PAP-A).
What are the indications for a "double test"?
Prenatal screening for trisomy I trimester of pregnancy is carried to all pregnant women. Specific indications include:
- women over the age of 35 years;
- the presence of a child (or a history — of the fetus aborted pregnancy) with genetically confirmed Down syndrome and other chromosomal diseases, congenital malformations;
- hereditary disease in the immediate family;
- radiation exposure or other harmful effects on one's spouse before conception.
At what stage of pregnancy is carried out I trimester prenatal screening?
Optimal timing of the survey — from 11 to 13 weeks of pregnancy.
What preparation is needed for a "double test» I trimester?
For this study, you must have the results of fetal ultrasound made no earlier than one week prior to analysis.
What are the dates of performance analysis?
How are the results of a "double test» I trimester?
The results of calculating the risk of chromosomal abnormalities are not the basis for a diagnosis, and are an indication for further special methods of investigation on the advice of the obstetrician-gynecologist.