Prenatal screening for trisomy I trimester of pregnancy (I trimester biochemical screening for pregnancy, "double test» I trimester) — complex research being undertaken to pregnant women to assess the risk of fetal abnormalities: Down syndrome (trisomy of chromosome 21), Edwards syndrome (trisomy 18), neural tube defects (NTDs).
What indicators are included in the "double test» I trimester?
- Human chorionic gonadotropin free (free hCG, free beta-hCG);
- Protein associated with pregnancy (PAP-A).
What are the indications for a "double test"?
Prenatal screening for trisomy I trimester of pregnancy is carried to all pregnant women. Specific indications include:
- women over the age of 35 years;
- the presence of a child (or a history — of the fetus aborted pregnancy) with genetically confirmed Down syndrome and other chromosomal diseases, congenital malformations;
- hereditary disease in the immediate family;
- radiation exposure or other harmful effects on one's spouse before conception.
At what stage of pregnancy is carried out I trimester prenatal screening?
Optimal timing of the survey — from 11 to 13 weeks of pregnancy.
What preparation is needed for a "double test» I trimester?
For this study, you must have the results of fetal ultrasound made no earlier than one week prior to analysis.
What are the dates of performance analysis?
1 day.
How are the results of a "double test» I trimester?
The results of calculating the risk of chromosomal abnormalities are not the basis for a diagnosis, and are an indication for further special methods of investigation on the advice of the obstetrician-gynecologist.
