Prenatal screening for trisomy II trimester of pregnancy

Prenatal screening for trisomy II trimester of pregnancy (biochemical screening II trimester of pregnancy, the "triple test» II trimester) — a set of research being undertaken to pregnant women in order to assess the risk of fetal anomalies — Down syndrome (trisomy of chromosome 21), Edwards syndrome (trisomy 18) neural tube defects (NTDs).

What indicators are included in the "triple test» II trimester?

  1. Human chorionic gonadotropin (hCG, beta-hCG); 
  2. Alpha-fetoprotein (AFP);
  3. Free estriol

What are the indications for "triple test"?

Prenatal screening for trisomy II trimesters of pregnancy is carried to all pregnant women. Specific indications include:

  • women over the age of 35 years;
  • the presence of a child (or a history — of the fetus aborted pregnancy) with genetically confirmed Down syndrome and other chromosomal diseases, congenital malformations;
  • hereditary disease in the immediate family;
  • radiation exposure or other harmful effects on one's spouse before conception.

At what stage of pregnancy is carried II trimester prenatal screening?

Optimal timing of the survey — from 16 to 18 weeks of pregnancy.

What should be the preparation for the "triple test» I trimester?

For this study, you must have the results of fetal ultrasound made no earlier than one week prior to analysis.

What are the dates of performance analysis?

1 day.

How are the results of the "triple test» I trimester?

The results of calculating the risk of chromosomal abnormalities are not the basis for a diagnosis, and are an indication for further special methods of investigation on the advice of the obstetrician-gynecologist.

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