In recent years, the steadily growing number of people suffering from diseases of the liver. According to WHO experts, these diseases in the world struck by more than two billion people. In Europe, one in five women and one in ten men are faced with diseases of the liver and biliary tract. Only in CIS countries each year from 500,000 to a million people with such diseases.
Only a small number of liver diseases are treatable. In most cases, liver damage leads to irreversible progressive reduction of its functions and, as a consequence, to the worsening of disability and reduced life expectancy. This is due to the fact that the liver is one of the most important and the most complex structure of organs and has a close functional relationship with almost all the other organs and tissues.
In fact, the liver is the central "biochemical factory" of the body — either in one body is not such an abundance of various enzyme systems. It is involved in the metabolism of all nutrients from their absorption in the intestine — whole blood flowing from the gastrointestinal tract (except oral and rectal cancer), before entering the general circulation passes through the body, where the pre-treatment of proteins, fats, carbohydrates, vitamins and other compounds.
The liver is also required for the synthesis of chemical compounds life: glycogen, cholesterol, fats, some hormones and precursors thereof, and blood proteins responsible for its clotting maintaining osmotic pressure, etc.
Another important function Liver — is defusing various toxic or do not relevant body substances as formed during the life (ammonia, "end-of" hormones, hemoglobin and other proteins) and received from the outside (polluting chemicals, food preservatives and colorants, and other alcohol drugs, medicaments, etc.).
In addition, the liver produces bile to emulsify the desired enteric received dietary fats. It collects and stores the blood supply (in case of bleeding), and substances such as glucose (in the form of glycogen), vitamins A, D, B12, minerals iron and copper. This body also plays an important role in immunity and the life cycle of red blood cells, in disease or removing the spleen liver takes over the majority of its "responsibilities".
Because of so many important functions of the liver and the small device is essential for life, and currently there are no devices or other methods to compensate for a little while multiple hepatic function.
These functions can be disrupted in a number of diseases: inflammation (hepatitis) caused by chemical injury, autoimmune reactions, viruses or bacteria, and non-inflammatory, such as hepatic steatosis. On the basis of these diseases, or for no apparent reason hepatic tissue can be replaced by an expanding connective tissue, which is accompanied by an increase in body size and the loss of its functions — a process known as cirrhosis, and it is impossible to draw. Also, the liver can affect malignant tumors, the most common of which — a very aggressive hepatocellular carcinoma.
The likelihood of developing irreversible liver damage increases significantly when exposed to air pollutants, water, food, many industrial chemicals as well as in viral hepatitis, alcoholism, drug abuse, regular use of greasy fried food, etc.
To alleviate the effect of these factors, and thus preserve liver in a functional state, has developed a number of drugs — hepatic (from the Greek hepar — The liver, and the Latin protectio — To protect). Today, they are virtually the only method of pharmacological effects on this vital Authority, since for most liver diseases targeted drug therapy does not exist.
Depending on the chemical structure and origin gepatoprotektory be divided into:
- Antioxidants of plant origin: of these most common drugs thistle — silibinin and others.
- Essential phospholipids — integral components of cell membranes.
- The amino acid derivatives to facilitate passage of chemical reactions in the liver: ademetionine, ornithine, etc.
- Bile acids, which improve on the current bile ducts and prevent the formation of gallstones: ursodeoxycholic acid.
In 2010, the family of hepatic replenished original domestic multi-component drug called "Remaksol." Its main active substance — Succinic acid — is a regulator of energy metabolism, stimulating energy-intensive chemical reactions through which the liver synthesizes the necessary materials and processing toxins. The action component of the drug not only improves the energy supply of the liver, but also has an antioxidant effect.
Most active substances occurs only when their delivery directly into the bloodstream, so the "Remaksol" is administered by intravenous drip infusion ("drip").
It should be remembered that no medicine can not fully protect the liver from the effects of disease, and can not recover its lost cells. Therefore, the main method of prevention of liver diseases is a healthy lifestyle, proper diet, moderation in alcohol consumption, abstinence, condom use (the most dangerous viral hepatitis are transmitted sexually and through injections of sterile syringes), the mandatory use of personal protective equipment when working with toxic substances — pesticides, paints, solvents, etc.
If you completely avoid contact with harmful substances to the liver fails, loosen their effects using gepatoprotektorov. To select the most appropriate in a particular case, the drug, you should consult with your doctor.
According to the materials LLC "NTFF" Polisan '"