In June 2012, molecular genetic sets "TromboGEN-RT», «FarmakoGEN-VKORC1» and «FarmakoGEN-CYP2C9» Group production companies Alcor Bio received CE-mark.
Diagnostic kit "TromboGEN-RT» is designed to detect hereditary thrombophilia and evaluation of the risk of deep vein thrombosis and pulmonary embolism. It allows you to identify single nucleotide change in the gene F5 (mutation Leiden) and in the gene F2 (prothrombin).
"FarmakoGEN-VKORC1» and «FarmakoGEN-CYP2C9» complement each other and are designed to determine individual susceptibility to indirect anticoagulants (warfarin). Diagnostic kits "FarmakoGEN-CYP2C9» and «FarmakoGEN-VKORC1» possible to determine single nucleotide gene replacement SYP2C9 (main metabolizing enzymes anticoagulants) and VKORC1 (epoxide — target actions anticoagulants). The presence of allelic variants of these genes leads to a significant change in the expected anticoagulant effect, which can cause serious complications.
Analysis using these three sets performed by polymerase chain reaction detection of accumulation of the product in real time (RT-PCR Real-Time) using allele-specific fluorescent probes. The main advantages format Real-Time PCR include: automation of the test procedure and to minimize manual handling, increase the reliability of the results, a substantial reduction in analysis time and the risk of errors, as in the course of this analysis, the risk of contaminations (sample contamination by foreign DNA molecules that distort the results of the analysis) is reduced to a minimum, as the influence of the human factor.
Currently, SC Alcor Bio — a developer and manufacturer of test systems for immunoassay and molecular genetic analysis — produces more than 60 kinds of products, 37 of them are CE marked.
Procedure for evaluating the compliance of the Civil Alcor Bio products with European quality standards conducted by MediMark Europe. CE marking — a sign indicating that the product meets the requirements of the European Union on security products. The practice of the CE marking of products was introduced in Western Europe in the mid-80s in order to increase the efficiency of the processes of trade between the EU and reduce the cost of compliance verification requirements for product safety for the consumer as set out in the Directives of the European Community. The CE mark is often referred to as "data sheet", which allows the manufacturer of any country in the world to sell their products on the European markets.