Siberian scientists have experienced the old pills

Siberian scientists, without waiting for clinical trials on himself tried to develop the product for the treatment of toxic liver cirrhosis, better known as the "tablet of old age", the developers claim that they have received a positive result met all expectations, the director of the company developing the drug "Scientific Future Management "Andrei Bekarev. 

New drug — a joint project of specialists of the Novosibirsk and Tomsk Institute of Pharmacology. According Bekareva, formal clinical drug trials on volunteers to start in November, and in pharmacy medication gets in a few years.

Invented and cured

The drug G5, which the media dubbed the "tablet of old age," Andrew Bekarev prefers to call the drug regenerative medicine, as its main feature — to return the body to restore function. Formulation increases the release of stem cells, which contribute to the restoration of organs and tissues. This property was discovered almost by accident by scientists.

"When we created the drug, he had a different purpose, it has been applied comprehensively with cytokines (regulators of immune reactions), we have data that can significantly reduce the dosage of these drugs in the treatment. When was described by the principle of action of the drug, it became clear that he effects may be more, "- said Bekarev.

When scientists realized the level of safety of the drug, they began to use it on himself, including medication consumed one of the founders of G5 — Research Institute of Pharmacology at the Tomsk Gleb Zyuz'kov.

"The other officer SRI was quite serious disease that has traditionally treatments, some adhesions, and he received a full recovery. But a single result does nothing, need a static sampling", — said the director of the development company.

Tablet from cirrhosis

According to the developers, pre-clinical testing of the drug in animals have shown that the G5 can heal such a widespread and intractable diseases like cirrhosis of liver toxicity. Mice injected with the drug completely restored liver cells.

"The drug has a greater effect, but the reception is chosen for one indication, as if SAID ten readings will spend one hundred years of testing," — said Bekarev.

The interviewee said that the choice is cirrhosis of the liver due to the possibility in this case more quickly release the drug into the market. In November, the developers have finished pre-clinical testing, and then send the document to the results of research in the Ministry of Health, and only when the agency will issue a permit, the researchers will begin clinical trials.

"According to the optimistic scenario for clinical trials will take one and a half to two years, according to the real — three to five years. Everything depends on the conditions presented by the Ministry of Health", — said Bekarev. According to him, probably, the drug will be available in the form of tablets or capsules, the cost will depend on the volume of production. "We will try to make it inexpensive" — promised the developer.

"Side Effects"

During preclinical drug scientists have found some of the "side effects" that may be the subject of future research.

"When testing for fetal toxicity of the drug effect on the course of pregnancy, we've got a curious result. Usually given a high dose of the drug, hooked already fertilized mouse egg, then look how many survived. Nearly 100% of oocytes developed grafted rose to adult mice "- told the agency.

Scientists have determined that the error occurred, and repeated the experiment. The results were confirmed in the future G5 to be studied as a treatment for the restoration of reproductive functions.

The sensation was another scientific experiment Siberians, with the results of which the media dubbed the drug "pill of old age." As the Bekarev, rodents 12 months of age were divided into control and experimental groups. The experimental group, the drug dripped into his mouth.

"From the age of 18 months there was a significant difference between mice. More than 30% of the control group died of old age, all of the mice showed signs of aging: baldness, arthritis legs, weight loss, changes in blood chemistry … An experienced group had a body weight twice higher than the control, rodents out the signs of aging, blood biochemistry analysis corresponded to healthy mice, "- he said.

The experiment was completed when the experimental group of mice lived for more than 21 months. Scientists decided to perform an experiment repeatedly been documenting it, not as a scientific experiment, but as a formal study.

Despite the incredible results, Andrew Bekarev stresses that is not going to market it, "pill for old age", as the test drugs on human beings as such, may take a hundred years.

Moreover, according to the businessman, there are many theories of aging. "Most G5 can improve the quality of life, not extend it. During aging are responsible not only stem cells," — said Bekarev.

RIA Novosti

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