Glomerulonephritis

Glomerulonephritis.  The renal glomerulus under the microscope.  Photo from http://academic.pg.cc.md.us

What is it?

Kidney consists of parenchyma (actually kidney tissue, where it is filtered urine) And pyelocaliceal system that collects urine and forwards into the ureter. In the parenchyma is a lot of capillary glomeruli (glomeruli), by which the "squeezed out" the liquid part of blood. It further by "loop" and is converted into urine.

In glomerulonephritis's own immune system, "confused" prior infection, attacks the cells of the glomeruli, causing their inflammation. This mechanism is characteristic of the disease and for rheumatism and other autoimmune diseases. Thus, glomerulonephritis— Is diffuse glomerular immune inflammation.

Glomerulonephritis can be acute or chronic, the latter is not necessarily the result of any other sharp-lobo process, and may be a separate primary disease.

Why did this happen?

Glomerulonephritis usually develops after a previous infection, usually strep — sore throat (tonsillitis), now rarely seen scarlet fever and others. In addition, the triggering factor could be infections such as malaria, brucellosis, measles, rubella, hepatitis, as well as a reaction to certain medications, foods, pollen, vaccines and organic solvents. An important role is played by hypothermia.

What if this happens?

So, if after 1-3 weeks after you have had a sore throat or other infectious disease, You started headaches, fever, increased blood pressure, it is possible that you sharp glomerulonephritis. In this case, because of the broken system is deteriorating renal filtration removal of fluid from the body, leading to edema. Often in acute glomerulonephritis decreased urination, and she urine takes the color of "meat slops" because of the impurities of red blood cells. Can begin abdominal pain and back pain, vomiting.

In chronic glomerulonephritis major simptomomi are persistent increase in blood pressure, often to high numbers, and swelling, more pronounced in the morning. Urine thus shows bias urine density and high protein content therein. Can significantly decrease the number of daily incontinence. In this case, pain in the kidney is not always, but if it happens then pulling or aching in nature.

And sharp, and chronic glomerulonephritis can occur in the latent (hidden) form, when the symptoms are scarce or nonexistent.

The more dangerous

In the absence or inadequate treatment leads to progressive glomerulonephritis, chronic renal failure. It ends up that man can not live without dialysis ("artificial kidney"), or organ transplantation.

Other hazards associated with 1) an increase in blood pressure, which leads to complications such as stroke and myocardial infarction, 2) poisoning of the body unhatched slag, which is manifested by toxic lesions of the internal organs, especially the central nervous system and intestines.

Diagnostics

At the first sign of the disease should consult a doctor, a nephrologist. To accurately determine the disease is necessary blood tests and urine tests, ultrasound of the kidneys do, the most accurate method of diagnosis is a biopsy of glomerulonephritis.

Treatment

The treatment of both acute and chronic glomerulonephritis should take place only under the supervision of a nephrologist, and in the acute phase — in a hospital setting. It is always complex, and includes a diet low in salt, medications (steroids and non-steroidal anti-inflammatory agents, cytotoxic agents, diuretics, antihypertensives). In severe renal insufficiency requires regular dialysis, and in severe cases — kidney transplantation.

Prophylaxis

If a person has chronic glomerulonephritis, he banned long trips, night shifts, work with toxic and other harmful substances. High blood pressure, symptoms of chronic kidney failure threaten to transfer a group of people with disability restrictions or outright bans employment. To prevent glorumelonefrita need time to treat infectious diseases, especially tonsillitis.

Like this post? Please share to your friends: