Hepatitis G

Hepatitis G

Hepatitis G (VGG) is ubiquitous. In Russia, the frequency of detection of the pathogen varies from 2% in Moscow to 8% in Yakutia.

The figurative expression of British doctors, hepatitis G — is the younger brother of hepatitis Hepatitis C. G is transmitted in the same way as the hepatitis C: a blood. The disease is widespread among drug addicts. It is also possible sexual transmission and transmission of the virus from mother to fetus.

Situations in which infection occurs most often:

  • Transfusion of blood. Worldwide, an average of 0,01-2% Of donors are carriers of hepatitis viruses, so now donated blood before transfusion recipient is examined for the presence of hepatitis viruses. The risk of infection is increased in patients who require repeated transfusions of blood or blood products.
  • Using a needle different people greatly increases the risk of infection. It is the most common route of infection with hepatitis G today.
  • Viruses can be transmitted by sexual contact, but the risk of transmission of hepatitis G virus through sexual contact is considered to be negligible.
  • The path of infection from mother to child (doctors call it a "vertical"). Approximately half of the children born to mothers with the presence of HCV RNA G, is also possible to identify this marker infektsii.Risk increases if the woman has an active form of the virus or the last months of pregnancy suffered a sharp hepatitis. The probability of infection of the fetus increases dramatically if the mother, except hepatitis B virus, has HIV infection. With the mother's milk virus HCV is transmitted.
  • Hepatitis G virus transmitted by tattooing, acupuncture, ear piercing non-sterile needles.

In 40% of cases the source of infection remains unknown.

What's going on?

In its manifestations reminiscent of hepatitis G hepatitis C. Together in order for it not characteristic inherent in the progression of hepatitis C infection with the development of liver cirrhosis and cancer.

Typically, acute hepatitis G can occur in symptomatic and asymptomatic.

Clinical manifestations of hepatitis G are not well understood.

The outcomes of the acute form of the disease may include: recovery, the formation of a chronic or long-term carriers of hepatitis B virus. A combination of hepatitis C can lead to cirrhosis.

Diagnosis and treatment

The main criteria for diagnosis are a variety of clinical and laboratory parameters: the markers of hepatitis viruses, changes in blood chemistry. For the diagnosis of hepatitis G method is used PCR (Polymerase chain reaction), which allows you to identify RNA HCV G.

The goals of treatment:

  1. Reduce or eliminate inflammation of liver, to prevent passage of hepatitis to cirrhosis.
  2. Reduce or eliminate the amount of virus in the body, particularly the liver.

The basis of all treatment options is interferon alpha. The mechanism of action of this preparation is to prevent the infection of new liver cells (hepatocytes).

Interferon can not guarantee complete recovery, but it prevents the development of cirrhosis and liver cancer. The effectiveness of treatment is significantly improved if interferon is used in combination with ribavirin. A positive effect is achieved in40-60% Of cases.

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